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Wuhan Topule Biopharmaceutical Co., Ltd

Hongshan District, Wuhan City, Hubei Province

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CAS: 1405-41-0,Gentamycin sulfate

Publisher:jinzun168Time:2023-05-30Number:2162

Basic information

cas: 1405-41-0

English name: Gentamicin Sulfate

English alias: Gentamicin sulfate; Gentamycin sulfate; Gentamicin sulfate salt;

Molecular formula: C60H127N15O26S

Molecular weight: 1506.80000

Accurate mass: 1505.88000

PSA: 719.38000

LOGP: -1.26180


Physicochemical property

Appearance and properties: White to yellowish powder odorless

Boiling point: 797.6ºC at 760 mmHg

Melting point: 218-237°C

Flash point: 436.2ºC

Stability: Stable under normal temperatures and pressures.

Storage condition: 2-8ºC

Safety information

RTECS number: LY2625000

Safety Description: S23-S36/37-S45-S22

Danger type code: R42/43

WGK Germany: 2

Customs Code: 2941901000

Dangerous Goods Mark: Xn

Production method and application

use

Purpose Gentamicin blocks the transfer of peptidyl-tRNA (Peptidyl-TrNA) from the recipient site to the donor site by inducing code misreading by binding to the 30S ribosomal subunit. The bactericidal effect of gentamicin on Pseudomonas depends on binding to the outer membrane part of the cell membrane, replacing the existing cations, making the membrane unstable and forming a cavity on the cell surface. Antibacterial spectrum: Gram-negative bacteria, staphylococcus and other Gram-positive bacteria.


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