Wuhan Topule Biopharmaceutical Co., Ltd
Hongshan District, Wuhan City, Hubei Province
Contact person:Manager Ma
English name: minoxidil
English alias: Regaine; Theroxidil; Minoximen; 2, 4 diamino - 6 - piperidino - pyrimidine - 3 - oxide; 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine; 6-(1-Piperidinyl)-2, 4-Pyrimidinediamine 3-oxide; 6-(1-Piperidinyl) Pyrimidine2,4-diamine 3-oxide; Rogaine; Alostil; 2, 6-diamino-4 -(piperidin-1-yl)pyrimidine 1-oxide; Loniten; 6-(1-Piperidinyl)-2, 4-Pyrimidinediamine 3-oxide; 6-(1-Piperidinyl) Pyrimidine2,4-diamine 3-oxide; Lonolox; 2, 6-diamino-4-piperidinopyrimidine 1-Oxide; Minoxidil; Tricoxidil;
Molecular formula: C9H15N5O
Molecular weight: 209.24800
Accurate mass: 209.12800
Appearance and properties: white crystalline powder
Density: 1.52g /cm3
Boiling point: 351.7ºC at 760 mmHg
Melting point: 272-274 °C (dec.)(lit.)
Flash point: 166.5ºC
Refractive index: 1.724
Stability: Stable at normal temperatures and pressures.
Keep in a cool, dry location. Keep containers closed when not in use. Protect from light. Keep in a cool, dry location. Keep containers closed when not in use. Protect from light.
RTECS number: UV8200000
Safety Description: S26-S36
Danger class code: R22; R36/37/38
WGK Germany: 3
Customs Code: 2933990090
Dangerous Goods Mark: Xn
Production method and application
4-chloro-2, 6-diaminopyrimidine (see 08910) was obtained from methyl cyanoacetate by cyclization and chlorination. It was then oxidized with perbenzoic acid to obtain 6-amino-1, 2-dihydro-1-hydroxy-2-imino-4-chloropyrimidine (C4H5CIN4O), and finally condensed with hexahydropyridine to produce minolidine.
Hypotensive drug for refractory, primary or renal hypertension. Used to prevent oil alopecia and animal husbandry.
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